P16.35 * DELAYED CONTRAST MRI FOR DIFFERENTIATING TUMOR FROM TREATMENT EFFECTS IN CONVENTIONAL AND ANTI-ANGIOGENIC TREATMENTS

Tumor Development under Combination Treatments with Anti-Angiogenic Therapies

Anti-tumor and Anti-angiogenic Ergosterols from Ganoderma lucidum

This study was carried out to isolate chemical constituents from the lipid enriched fraction of Ganoderma lucidum extract and to evaluate their anti-proliferative effect on tumor cells and human umbilical vein endothelial cells (HUVECs). Ergosterol derivatives (1-14) were isolated and purified from the lipid enriched fraction of G. lucidum. Their chemical structures were established by spectros...

Diffusion-weighted MRI for differentiating Wilms tumor from neuroblastoma.

PURPOSE Wilms tumor (WT) and neuroblastoma (NB) are the most common pediatric abdominal malignant neoplasms of the kidney and adrenal gland. Differentiating them from each other is essential since their treatments are different. Here, we aimed to show the diffusion characteristics of WT and NB for differentiation. METHODS Diffusion-weighted imaging (DWI) of 17 histopathologically diagnosed le...

Delayed phases of contrast MRI, can it be valuable in multiple sclerosis active phase diagnosis?

Background: Observing the enhancing plaques in magnetic resonance imaging (MRI) is one of the most valuable diagnostic modalities in confirming the diagnosis of multiple sclerosis (MS), its recurrence and for better detection of active disease. Since active lesions discovery can improve designating diffusion in time diagnosis of MS and controlling disease activity, and there is not any definite...

Multi-input Optimal Control Problems for Combined Tumor Anti-angiogenic and Radiotherapy Treatments

Abstract. A cell-population based model for tumor growth under anti-angiogenic treatment with the tumor volume and its variable carrying capacity as variables is combined with the linear-quadratic model for damage done by radiation ionization. The resulting multi-input system is analyzed as an optimal control problem with the objective of minimizing the tumor volume subject to isoperimetric con...